Avalanche's DeFi ecosystem demonstrates explosive growth and dynamic user engagement in 2024, with Aave v3 emerging as the dominant lending platform. The blockchain experienced a remarkable 1,500% surge in lending volume from $100M to over $1.5B, driven by significant increases in deposit, borrow, and flash loan activities. USDC and USDC.e stablecoins lead the market, representing 91.5% of total $138B stablecoin activity, while Aave v3 commands 41% of total lending volume at $67.3B. User participation remains volatile but highly active, with weekly unique users fluctuating between 1,100 and 4,073, indicating a rapidly evolving and increasingly sophisticated DeFi landscape on the Avalanche blockchain.